Clinically significant depression is marked by persistent sadness, a depressed mood, diminished interest in previously enjoyable activities, and other symptoms that interfere with the ability to function in daily life.
The condition often arises from a complex combination of factors that can include genetics, family history, trauma, stress, and illness. It is one of the most common mental disorders as nearly 1 in 5 adults in the United States have been diagnosed with depression in their lifetime.
Fortunately, effective treatments are available including medications, psychotherapy, or a combination of the two. Self-help strategies can also help people better cope with their symptoms and begin to feel better.
Living With Depression
![Depressed woman lying on the bed at home.](https://www.verywellmind.com/thmb/Aq5gBTlA6ErscfRkQiF2mRgygUU=/600x450/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1433295949-972b0aca6cf841fda774bc941be96c99.jpg)
![a couple and their kid together](https://www.verywellmind.com/thmb/SeW6tm-o-Nhr5wmPw6gJLlipldw=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/relationships-and-depression-10-tips-to-cope-1067466_final-1e6689418354424a836542e2a3c1b813-7c36168ef15445c69aeebdf1098794c1.png)
![Insomnia](https://www.verywellmind.com/thmb/dlUwPUmD3qNo3ctGbotw0IxG1dI=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-12627905461-8242e03290d94a8b8c92c8decba1f491.jpg)
![Woman looking at her phone with notification icons and chat bubbles popping up](https://www.verywellmind.com/thmb/uWsbtD-Grp70Mr5xkbUuz6da6Js=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/evolvingtechnology-recirc1-06f70e12e46e4a8b9d76aea666057368-dcc97d6b017941e4ad30a1eedd1479df.jpg)
![Depression is linked to borderline personality disorder.](https://www.verywellmind.com/thmb/2GVtUVmh9TqdCJbuQgw9ZbniCqs=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/depression-569a3c5a3df78cafda911bb9.jpg)
![Woman researching on laptop](https://www.verywellmind.com/thmb/Xbf1ZsUwRNYDbo8lrbFizNkaGoI=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/BestOnlineHelpforDepression_edit-646417583ee5425bad48968b330eede0.jpg)
Frequently Asked Questions
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Appropriate treatment for depression is essential, but self-help strategies can also help you feel better. Some things that can help you cope with feelings of depression include getting enough sleep, eating a healthy diet, finding social support, and engaging in regular physical activity. While depression can make these things more challenging, tackling one or two tasks each day can help improve your well-being.
Learn More: Ways to Cope When You Have Depression -
Some ways that you can support a friend or loved one with depression include offering support and avoiding judgment. Offer to help with tasks that your friend might be struggling with. Let them know you care, ask them what you can do to help, and encourage them to talk to their doctor. Learn more about depression so you can better understand ways you can help.
Learn More: What to Say When Someone Is Depressed -
While depression appears to have some genetic risk factors, there is no identifiable gene for depression. However, research suggests that it is the interaction of genetics and environmental factors that contribute to the condition’s onset. You may have a genetic predisposition to depression, but this does not necessarily mean that you will develop the condition.
Learn More: How Genetics Factors Into Depression -
While there is no “cure” for depression, it is a treatable condition that can often be alleviated with the use of medications, psychotherapy, and lifestyle modifications. Antidepressants can be effective, but they often take some time to begin working. While such medications may be used alone, they are also often prescribed in conjunction with psychotherapy.
Learn More: Can Antidepressants Cure Depression?
Key Terms
- Mood Disorder
A mood disorder refers to a broad class of mental health conditions, including depression and bipolar disorder, that primarily impact emotional states. People may experience prolonged periods of a significantly depressed or sad mood, or they may have episodes of an abnormally elevated or irritable mood to an extent that it causes distress and interferes with daily living.
- Psychiatric Evaluation
A psychiatric evaluation is an assessment utilized by psychiatrists to diagnose mental health conditions. An evaluation often involves talking to your doctor about your symptoms, getting a physical exam, and filling out a questionnaire. This allows your doctor to gain insight into the nature and severity of your condition.
- Dysthymia
Persistent depressive disorder (PDD), previously known as dysthymia, is a chronic state of depression. It involves symptoms such as low mood, loss of interest, sleep changes, and appetite changes that last for at least two years. Symptoms may vary in intensity over time.
- Psychosis
Psychosis is a mental state that involves losing contact with reality. People who experience psychosis may believe, see, hear, or feel things that are not real. Psychotic depression is a condition in which people experience psychotic symptoms such delusions and hallucinations alongside symptoms of depression.
- Seasonal Affective Disorder
Seasonal affective disorder (SAD), formally known as major depressive disorder with a seasonal pattern, is a mood disorder that occurs the same time each year. People may experience feelings of depression, social withdrawal, and fatigue usually during the fall and winter. Disruptions to the normal circadian rhythm, often associated with reduced sunlight, may contribute to the condition’s onset.
- Postpartum Depression
Postpartum depression, formally known as major depressive disorder with a peripartum onset, is a serious but treatable form of depression that generally occurs after giving birth. It can potentially present with psychotic features and is characterized by symptoms such as sadness, fatigue, poor sleep, trouble bonding with the baby, feelings of guilt, and intrusive thoughts.
Explore Depression
![Jeremy Nobel](https://www.verywellmind.com/thmb/h_g-qe1ohFQ6P1YoH2nLM_HMZTg=/600x450/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/primary56-a4f25b34950e4f358f590d91746f3cb7.png)
![Psychiatrist taking notes while listening to female patient](https://www.verywellmind.com/thmb/02GikuPacWv-HHdL7m4bU4A0BYA=/600x450/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/Primary-Image-best-online-psychiatry-that-takes-insurance-of-2023-7254902-300003cd4255496db8e8600618cc81fb.jpg)
![Person meditating on top of the bed cross-legged position](https://www.verywellmind.com/thmb/rASpj8KhNZCy1AKmfbMkYJbOBTE=/600x450/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/VWM-depression-meditation-stocksy-2-A1-f8cde6d25e5749079b274af4f9efe45f.jpg)
![person depressed at work](https://www.verywellmind.com/thmb/Oe5sCNHfQDBbn_5DXNlXq6hOG8Q=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-948421446-9e5ac88a2b8942c9a70725eed0ff6846.jpg)
![Young Black man talks with a female therapist](https://www.verywellmind.com/thmb/RuNPRQBhfyM_y_CtiTUj7cWTjkw=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1499175019-bbb4321d91084623a56c9adf64f157c0.jpg)
![sad woman on the steps](https://www.verywellmind.com/thmb/Guf6gq4ZlYyIO7RbhTHl7oLB3cw=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1349024749-581b10cb8de94b19a6b49624695c002a.jpg)
![Woman with rain clouds over her head](https://www.verywellmind.com/thmb/rPKVEPJkyzGQVji4OjZg4DUwrTk=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/Xthingspeoplegetwrongaboutdepression-v22-c61c343949384cbfabf517ec3a8a91a1.png)
![person looking sad on bed](https://www.verywellmind.com/thmb/OIArV5k0fY2td1C1jBVgBKtSf_E=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1421877961-694529fa1d56463ebbf056e204866d6e.jpg)
![group therapy session](https://www.verywellmind.com/thmb/6lS7nykFWA0X10IcqZhXwU8vtfU=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1130406826-cf0e9fbdced241f8b572ed65d2461da7.jpg)
![Shot of a young woman looking depressed at home](https://www.verywellmind.com/thmb/X9ZJUQeM_LNOlDjJoAMq6LIU20U=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1369775929-548043a3050e425190d0f9680d713b73.jpg)
![person looking out the window](https://www.verywellmind.com/thmb/h_CoLcRkXCv7IyfB_v-L32FQL9c=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1356429549-1e364e925569479984fe206067d12f77.jpg)
![friends comforting each other](https://www.verywellmind.com/thmb/Ad932GrMyq3jcgyqpXkXgXPgARs=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/Friend-loss-to-suicide-Color-20269284b8704bafadeda9c9b35d44cf.jpg)
![Shot of a young businesswoman looking stressed while using a laptop during a late night at work](https://www.verywellmind.com/thmb/2bVcIuVbqDFGqhlCCGSgkfTx5vQ=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1298273162-376fc33195c2446c9d010bcc971689e4.jpg)
![person depressed hugging their pillow on a couch](https://www.verywellmind.com/thmb/w56ihhLLcEd6_iowVgonAvIkSQ0=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-728909107-1a7110c2d879424c9399bf3ac88d1546.jpg)
![person stressed at work](https://www.verywellmind.com/thmb/A9KrAKJYC2kFqOyG99EtN1kpQi8=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1298252213-881dc57e798841c88fd89dd7d2a841fc.jpg)
![woman laying on bed thinking about life](https://www.verywellmind.com/thmb/vmdhDkJZ8VOn8UIRFjQwR_2xx68=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-633710687-1607dddd2e1c4ea2a1474a844b4ed2af.jpg)
![stressed person at work with glasses on](https://www.verywellmind.com/thmb/p1gpV6Sz2UkM9ULBqiQIuG67cdo=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1132977608-ef381118979844d7bae0f78a4749af8f.jpg)
![depressed person in a support group](https://www.verywellmind.com/thmb/SrbU9QQgHtQgVjUY6SCQ_aeNX3Y=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1048189084-9a67dfe38b084bdfb82ea05d7638c99d.jpg)
![women tired at her desk](https://www.verywellmind.com/thmb/sFcLdWZkhmbAb44y1qWpoqZZXGg=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-12153818831-8860955a6be241f39d87bd4604da3e2f.jpg)
![Doctor with checklist for depression](https://www.verywellmind.com/thmb/OUa7md7d65OG5Tn6jgNcRdUc0nU=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1342251993-f62eda7a1d8d4e2eae914cd96d96873d.jpg)
![Older lady looking at photos on the couch](https://www.verywellmind.com/thmb/uj4aUbfRE-W-iaTND96ZUwmNx7o=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-182657415-2cec1044cd6540a3bb6811b6e7ec8e53.jpg)
![Woman lying on the couch depressed.](https://www.verywellmind.com/thmb/YiGua8DcsNDcGylLIPTczB6W3KQ=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1366023753-846cf46a099a4492bb659f8fe52db3c4.jpg)
![older person depressed while thinking on their bed](https://www.verywellmind.com/thmb/xTcKaXzOFSguTa1CM8aPwgwssxQ=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1217126168-601c44a9dd17458a985c5edc3174c7d5.jpg)
![Indoor, serene young man resting head on hand and thinking](https://www.verywellmind.com/thmb/O_-gFI4dBHk-0_8WPHnF4e44Dc0=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-506326438-a9e815e7628c439daa9cf2ce01daef57.jpg)
![Young woman with COVID-19 symptoms resting in bed](https://www.verywellmind.com/thmb/Al8z8IcUxdj3nUBohN-yg1MHEUY=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-13112833131-79328e073be4454fb8285f12e32730cd.jpg)
![Young woman lying on her back with tear running down her cheek eyes closed](https://www.verywellmind.com/thmb/LixBshYYq2r_85vu-F5oz9JaSnQ=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1336164328-ed1abf4eaa9b4e418c53883b8d41d79c.jpg)
![BIPOC woman taking a pill](https://www.verywellmind.com/thmb/Dayej15UJGHQXjNaEll9Usemq2Y=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1278631117-ca7f6e124c514a7f9e9b16f10da74506.jpg)
![BIPOC woman looking depressed](https://www.verywellmind.com/thmb/lNQHDuBrOzw6nKta6Yo2RHWGYDg=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-520792461-a0acae7dbbab4a0a838846e7c2151d78.jpg)
![Man laying in the grass staring at the sky while others around him play](https://www.verywellmind.com/thmb/dFtTY1Hx-mqTUF1kEFdL7Ia7sw0=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/why-do-i-feel-dead-inside-5210393_color_v1-02bfc2167ef848e7962f33b2446c581a.png)
![Low Section Rear View Of Man Walking On Footpath By Fallen Autumn Leaves](https://www.verywellmind.com/thmb/i2DEZyb8p-1mx6WTuuTsIbxtWwk=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1165273543-701881fd5ee8427eb5ef2ea23a3291e5.jpg)
![Close-up of sad woman lying on sofa at home](https://www.verywellmind.com/thmb/wvWuNz_TGyndwWGLoHcWQ3m_fuk=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/cns-depression-0a7df9e007c646ff97a5b34f8d4087a4.jpg)
![depressed man sitting in room](https://www.verywellmind.com/thmb/2mwL3wEhAEfhXll4piA6-1S-YSo=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1277201995-964696c0a5fe4e659cf854bfa4573468.jpg)
![Two friends greeting each other and embracing outside a restaurant](https://www.verywellmind.com/thmb/ZH0rVaO_Q4qNnM6W-uRFT6LaMWY=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1034326514-ff557f26627f46ff86df8d2fd6d74f56.jpg)
![sad woman looking out the window](https://www.verywellmind.com/thmb/K9XydAwMFOtA2ll-1ls4nqRefsk=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-11296966691-8766899973cd4acdb0b26e6e1e5b2937.jpg)
![Causes for birthday depression](https://www.verywellmind.com/thmb/OUuXY4KMJCpx67g2XeVnKG027k4=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/birthday-depression-why-some-people-feel-sad-on-their-birthdays-5190225_final_nologonotext-9583b965b6624ef0a5b7397f95ff0612.png)
![father looks out the window in his home as he carries his baby daughter.](https://www.verywellmind.com/thmb/bRc0WHYDkprOz1hH8HRcwjfD_Kk=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1371356377-a923f2c1727e4a01b6e5d2e5356ed7b2.jpg)
![Ways to talk to your partner about depression](https://www.verywellmind.com/thmb/hOfUhqfWODum6DHtSf5ok16kGak=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/HowtoTalktoYourPartnerAboutYourDepression_notext_color_FINAL-500d72428068463fbaa0fa5b84d555f3.png)
![Upset couple sitting in bedroom.](https://www.verywellmind.com/thmb/STk6TuIE0K89kbhygw_u02fXQkM=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-12083737631-3dd6f06a7fca4fd8a82bd23dd48a61af.jpg)
![Woman taking pill with a glass of water](https://www.verywellmind.com/thmb/FtWHrw4X1k59ayOIaybffwUp1t4=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-1182285243-fcfa18e81ea742ae932201ddd6043411.jpg)
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![The DSM-5 made some changes to the diagnosis of depression.](https://www.verywellmind.com/thmb/cdXtoukA6o7sj_LP5Eg6U5Tcx8M=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/GettyImages-672153439-5aa30a39642dca003625db13.jpg)
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![Common types of treatment for depression](https://www.verywellmind.com/thmb/Y72ecRMxc3ZX4z9wQR7KuT81sb8=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/treatments-for-depression-1065502-b0d9977b90cd4827a9bb1f3fbd047afb.png)
![Common types of depression](https://www.verywellmind.com/thmb/aWecNKjZI0kWfJg-H_7N1M2mIIY=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/common-types-of-depression-1067313_V3-c0654a8dc19049a086684d391318514f.png)
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![help hotlines to call](https://www.verywellmind.com/thmb/yeCkdpSbrIV0LyBiLhIaetI0gBE=/400x300/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)/National-helpline-database-4799696-V1-no-text-be86ec92e24c4cd08f472592b3d81f46.png)
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