How to Treat Post-Inflammatory Hyperpigmentation

Post-inflammatory hyperpigmentation (PIH) is an area of darker skin where acne or a wound has healed. The discoloration is due to excess melanin (pigment) produced as part of the skin's natural response to inflammation, or due to pigment dropout (melanin entering the dermal layer of the skin).

This article explains post-inflammatory hyperpigmentation, why those dark spots develop, and what you can do to help them fade faster.

Post-Inflammatory Hyperpigmentation Symptoms

PIH usually looks like a flat area of discoloration on the skin. It can appear white, pink, red, purple, brown, or black, depending on your skin tone and the depth of the discoloration.

PIH can develop in all skin types. However, it tends to be more severe and longer-lasting for people with medium to dark complexions. People with skin of color have more pigment (melanin), so there is more of a chance of PIH with certain skin problems. PIH affects both men and women.

Causes of Post-Inflammatory Hyperpigmentation

PIH develops when a wound or irritation, like a scrape, rash, or pimple, causes the skin to become inflamed. As the skin heals, it produces too much melanin (the protein that gives the skin its color). This darkens the skin.

Most people with acne have some degree of PIH. And it's not just the significant blemishes that cause these spots—hyperpigmentation can follow even relatively minor pimples and blemishes.

That said, the more inflamed a breakout, the larger and darker the PIH spot tends to be. In addition, picking or popping a pimple increases the chance of developing PIH because it increases inflammation.

Other causes of PIH include:

• Sunburn
• Chemical peels
• Dermabrasion
• Laser resurfacing

Acne Scars vs. Post-Inflammatory Hyperpigmentation

You may be relieved to learn that PIH is not true scarring. In fact, people often call it "pseudo scarring" because although it leaves a mark on the skin for a while, it does not damage the follicle.

True acne scars occur when there is either a loss of tissue, causing a pitted or depressed area, or an overgrowth of tissue leaving a raised scar. PIH, on the other hand, is flat. It's not pitted or raised, but rather simply darker than the surrounding skin.

Hyperpigmentation Acne Treatment

Whatever treatment option you choose, understand that improvement will take time. PIH usually goes away on its own, but it can take several months to years to fade completely. Topical medications and in-office treatments can help speed this up.

This is not a comprehensive list. Your healthcare provider can guide you through all the possible options to properly treat your skin.

Alpha Hydroxy Acids (AHAs)

Alpha hydroxy acids, especially glycolic acid, are a good starting point for treatment. Alpha hydroxy acids (AHAs) help speed up the skin's natural exfoliation process, which can help improve the look of PIH.

You can find these ingredients in many OTC "brightening" treatments. In addition, leave-on treatments like lotions, creams, and gels will give you better results than wash-off products like cleansers.

Other OTC ingredients that can help fade hyperpigmentation include:

• N-acetyl glucosamine
• Niacinamide
• Vitamins A and C

Hydroquinone

Hydroquinone is a widely used treatment for PIH. It's only available by prescription in the United States. Hydroquinone blocks the enzyme responsible for melanin production, thereby lightening the skin.

These creams often contain additional lightening ingredients, which can give better results than hydroquinone alone. Ingredients combined with hydroquinone include:

• Kojic acid (a chemical made from fungi)
• Glycolic acid
• Tretinoin and other retinoids
• Vitamin C

Topical Retinoids

Dermatologists often prescribe topical retinoids to treat acne. That's because retinoids help clear acne by speeding up cell turnover rates. This rapid exfoliation can also help fade PIH.

Retinoid creams include:

• Retin-A (tretinoin)
• Retin-A Micro
• Tazorac (tazarotene)
• Differin (adapalene)

Except for Differin, these medications are available by prescription only. Like other treatments, it may take several weeks to months to see noticeable results.

When using these treatments, look for excessive dryness, redness, and irritation, as this can trigger PIH on its own.

Azelaic Acid

Azelaic acid is another medication used to treat acne and PIH. It works by decreasing inflammation and speeding up cell turnover rates. People sometimes use azelaic acid along with glycolic acid or tretinoin.

Some studies have shown azelaic acid to be as effective as hydroquinone at treating hyperpigmentation. Therefore, it is a good alternative for those who can't use hydroquinone.

Fading Over Time

The good news is that PIH can fade away over time, even without treatment. But time is the operative word. PIH can take three to 24 months to disappear entirely, or even longer in some cases.

PIH doesn't always fade away on its own. In some cases, it's more or less permanent.

Some treatments will help. Some may not wholly erase dark marks, but they might at least lighten them considerably. Therapy can also help speed up fade time if you're not keen to wait for spots to lighten naturally.

Over-the-counter (OTC) products can help fade more subtle marks. However, a prescription cream might be a better choice for deeper marks or those that have been around for a long time. Your dermatologist has a lot of products that can do the trick.

In-Office Treatments

More persistent cases of PIH can be treated professionally at your dermatologist's office. Treatments include:

• Chemical peels
• Lasers
• Microneedling
• Microdermabrasion

Just one treatment isn't enough to fade hyperpigmentation. You'll likely need a series of treatments spaced two to four weeks apart (depending on the procedure you're having done). Your healthcare provider can help determine which of these treatments, if any, would be most effective for you.

How to Get the Best Results

To get the best results possible, keep a few things in mind to help prepare your skin for whichever treatment you choose.

Control Your Acne

Before treatment, your acne should be under control. Otherwise, each new pimple could cause another dark spot, and you would never get ahead of the curve (and never see the clear, even skin tone you're looking for).

Over-the-counter acne products are effective for treating mild acne. However, you may need to treat more stubborn or severe breakouts with prescription acne medications if you want to see real improvement.

Use Sunscreen

Use sunscreen every day and a sunhat as well. The sun may darken the discolorations and make them fade more slowly. Plus, many PIH treatments (and many acne treatments) can make your skin more sensitive to the sun.

If you're worried that sunscreen could make your breakouts worse, don't be. There are many sunscreens for breakout-prone skin.

Monitor Your Skin

Monitor your skin for irritation. Although treatments are helping you clear your skin, acne and PIH treatments also have the potential for irritation.

Unfortunately, irritated skin could lead to even more dark spots and uneven skin tone. If PIH is a problem for you, let your healthcare provider know if your skin becomes irritated from your acne treatments.

Summary

PIH is dark spots left on the skin after a pimple heals. It doesn't damage the skin, so it doesn't cause pits or raised scars on the skin.

PIH usually heals over time without treatment, but it can take up to a couple of years or sometimes longer. Some spots may never fade. Treatments include OTC creams, prescription medications, and in-office procedures.

To get the best results from treatment, be sure your acne is under control and use sunscreen. During treatment, carefully watch your skin for irritation.